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After trimming the hair at the kidney position on the back of the rat, fix it. Under ether anesthesia, an incision was made at the left dorsal kidney position (in the sham surgery group, only the incision was made and the kidney was not cut). After f...
2024-09-24BB Wistar rat is a spontaneous diabetes animal model...
2024-09-23The model of heart failure caused by blood volume overload can be divided into acute and chronic types. The acute blood volume overload model is commonly used in animals with already heart failure, usually by rapidly inputting colloidal solution to a...
2024-09-23Administer 60mg/kg pentylenetetrazol or 200mg/kg nicotine intravenously to animals...
2024-09-23Selecting albino guinea pigs as experimental subjects, the bacterial suspension was intraperitoneally inoculated into guinea pigs at a dilution of 2 × 10000000 CFU/ml...
2024-09-23By detecting the matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in conjunctival tissue cells of diabetes rabbits fed with high-fat and high-sugar diet plus streptozotocin, the relationship between them and...
2024-09-23SD rats were intraperitoneally injected with a 5% pentobarbital sodium physiological saline solution at a dose of 40-50 mg/kg body weight. The rats were fixed in a dorsal position on a surgical plate, and their abdomen was shaved and disinfected with...
2024-09-23Ten tree shrews were used. For the first time, 0.5ml of serum (1 × 10 ^ 8 CID, chimpanzee infection dose) was intravenously injected from two asymptomatic human carriers of hepatitis B virus. Three days later, an equal amount of the same human serum ...
2024-09-23Bufalin tincture has strong irritant properties and can stimulate the conjunctiva of rabbit eyes, causing certain degree of damage, thus replicating the acute irritant conjunctivitis model in rabbits...
2024-09-23Take sterile naturally dried blood clots from the same type of rats, grind them and sieve them through a 200 μ m sieve for later use. When applied, take 0.5ml of physiological saline and 100mg of blood clot homogenate to prepare a suspension. Measure...
2024-09-23Adult hybrid dogs weighing 10-15kg, intramuscular injection of 30mg/kg body weight of 3% pentobarbital sodium, tracheal intubation. One side of the femoral artery and vein were respectively intubated to measure arterial pressure and collect blood sam...
2024-09-23Acanthamoeba keratitis is a rare and severe chronic progressive corneal disease...
2024-09-23Adult healthy New Zealand white rabbits, with an average weight of 2.3kg, half male and half female; Medications: 10% chloral hydrate, 75% alcohol, iodine, penicillin...
2024-09-23Surgery was performed under intraperitoneal anesthesia with pentobarbital (0.4mg/kg) and sterile conditions. A longitudinal incision was made on the lateral side of the left lower limb of the animal, and a specially designed vascular clamp was used...
2024-09-23Wistar rats were intraperitoneally injected with doxorubicin at a dose of 2.5mg/(kg · time), 3 times per week, with an interval of 2 weeks, followed by 1 week for a total of 6 times, with a total dose of 15mg/kg. After the last injection was complete...
2024-09-23Bruning et al. introduced ineffective alleles of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1) into mice through double heterozygosity, resulting in a decrease in IR/IRS-1 expression in the mice...
2024-09-23