[Animal Modeling - Drug Efficacy Evaluation] - Traditional Chinese Medicine Exercise Fatigue Animal Model

The replication method used male Wister rats weighing 180-200g. Mix rhubarb, saltpeter, and standard feed evenly in a ratio of 0.85:0.15:9.0 to make medicinal feed...

2024-08-21

[Animal Modeling - Efficacy Evaluation] - Other Gene Knockout and Transgenic Animal Models

Progressive myoclonic epilepsy (PME) syndrome model, also known as cystatin B gene knockout mouse model...

2024-08-21

[Animal Modeling Drug Efficacy ]-Evaluation Gene Knockout Epilepsy Model

Mainly using gene knockout and transgenic technology for model replication...

2024-08-21

[Animal Modeling Drug Efficacy Evaluation] - Epilepsy like Mouse Primary Epilepsy Model

Measure the degree of seizures in mice before the experiment and select qualified animals for the experiment...

2024-08-21

[Animal Modeling - Drug Efficacy Evaluation] - Mongolian Gerbil Hereditary Epilepsy Model

　　Mongolian sand rats that are sensitive to attacks will be individually housed in separate cages and given free access to food and water. In addition to general hygiene requirements, indoor spaces should be kept quiet, and no noise or movement of ca...

2024-08-21

[Animal Modeling Drug Efficacy Evaluation] - Chronic Experimental Epilepsy Model Induced by Cobalt

Healthy rats weighing 200-300g can be used in females or cats. Anesthetize by intraperitoneal injection of chloral hydrate (dose 350-400 mg/kg body weight) or pentobarbital sodium (dose 50-60 mg/kg body weight)...

2024-08-21

[Animal Modeling - Efficacy Evaluation] - Transgenic Animal Models

The model is mainly established using genetically modified technology...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Rat Cerebral Vasospasm Model

The replication method used to create a DCV model in rats after subarachnoid hemorrhage by inserting a catheter through the frontal subarachnoid space and injecting blood twice directly into the Willis circle of the cerebral artery...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Mouse Cerebral Vasospasm Model

The replication of SAH was anesthetized by intraperitoneal injection of pentobarbital sodium (60mg/kg body weight), and the skin in the surgical area was disinfected...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Canine Intracranial Hypertension Model

Healthy domestic dogs, weighing 10-20kg. Anesthesia with intravenous injection of pentobarbital sodium at a dose of 30mg/kg body weight...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Rabbit Intracranial Hypertension Model

New Zealand rabbits, male or female, weighing 2.0-2.5kg. After intravenous injection of pentobarbital sodium (at a dose of 25-30mg/kg body weight) or 20% Uratan (at a dose of 5ml/kg body weight) through the ear vein, anesthesia was administered. The ...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Brain Hematoma Animal Model

The evolution of cerebral hematoma is a very complex process, and it is often difficult to conduct systematic research on this process from a clinical perspective...

2024-08-21

[Animal Modeling - Pharmacological Evaluation]- Venous Thrombosis Animal Model

Venous thrombosis is closely related to slow blood flow, increased coagulation factor activity, and vascular wall damage. Therefore, experimental models of venous thrombosis can be formed by methods such as ligation of veins, interruption or obstruct...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Cerebral Arteriovenous Malformation

The previous animal models of cerebral arteriovenous malformations were arteriovenous fistulas without a true malformation mass structure. Massoud et al. established for the first time in 1994 an animal model of cerebral arteriovenous malformation co...

2024-08-21

[Animal Modeling - Pharmacological Evaluation] - Brain Ischemic Tolerance Animal Model

The phenomenon of cerebral ischemic tolerance refers to the pre production of sublethal ischemia in the brain. This increases the tolerance of brain neurons to subsequent lethal ischemia, thereby preventing the occurrence of delayed neuronal death af...

2024-08-21

【Animal modeling - Drug efficacy evaluation】 - Focal nephritis model

dog; Medications: Pentobarbital, hot water, turpentine...

2024-08-21