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[Animal modeling] - Study on the control and optimization of rat oral ulcer animal model by chemical burning method

[Animal modeling] - Study on the control and optimization of rat oral ulcer animal model by chemical burning method

To establish an animal model of oral ulcer in SD rats by different chemical burning methods and screen the best scheme for the evaluation of therapeutic effect...

2023-12-02
[Animal modeling] Screening of differentially expressed genes and functional analysis in APP/PS1 Alzheimer\\

[Animal modeling] Screening of differentially expressed genes and functional analysis in APP/PS1 Alzheimer\\

To analyze the differentially expressed genes in the prefrontal cortex of Alzheimer\\\'s disease (AD) model mice and reveal the pathogenesis of AD from the transcriptome level...

2023-12-02
【Animal Modeling】-Biosafety and Data Quality Considerations for Animal Experiments on Highly Infectious Drugs in ABSL-3 Facility

【Animal Modeling】-Biosafety and Data Quality Considerations for Animal Experiments on Highly Infectious Drugs in ABSL-3 Facility

Animal models are the key to the study of serious infectious diseases, and are of great significance to determine the pathogenesis of the disease and develop vaccines and drugs...

2023-11-30
[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...

2023-11-30
【Animal Modeling】 - Establishing Humans α A Parkinson\'s disease rat model with synaptic nuclear protein A30P mutation

【Animal Modeling】 - Establishing Humans α A Parkinson\'s disease rat model with synaptic nuclear protein A30P mutation

Founder α⁃ Parkinson\\\\\\\'s disease model of transgenic rats with synaptonuclein A30P mutant...

2023-11-30
[Animal modeling] - Establishment and evaluation of rat model of acute lung injury caused by smoke inhalation of simulated ship fire

[Animal modeling] - Establishment and evaluation of rat model of acute lung injury caused by smoke inhalation of simulated ship fire

To establish a rat model of acute lung injury (ALI) induced by smoke inhalation from ship fire with multiple composite materials as combustor and temperature controlled...

2023-11-30
[Animal Modeling] - Marmot Hepatitis Virus Model

[Animal Modeling] - Marmot Hepatitis Virus Model

Groundhog, also known as marmot. The average weight of a groundhog is 4.5kg, and it can grow up to 6.5kg at most, with a body length of approximately 56cm. The groundhog is mainly distributed in the grasslands of North America to Canada and other reg...

2023-11-27
[Animal Modeling] - Research on Renal Vascular Hypertension Animal Model

[Animal Modeling] - Research on Renal Vascular Hypertension Animal Model

Renal vascular hypertension is the most common secondary hypertension caused by narrowing or obstruction of one or both renal artery trunks or branches, resulting in reduced renal vascular flow and renal ischemia. Renal vascular hypertension accounts...

2023-11-27
[Animal modeling] - KK mice with hereditary diabetes

[Animal modeling] - KK mice with hereditary diabetes

he KK mouse was successfully cultivated in 1957 by Japan\'s Konteng family using the original Japanese mouse (also known as the \"twenty day mouse\"). In 1962, Nakamura reported that KK mice had similar properties to adult obese diabetes, w...

2023-11-27
【Animal Modeling】 - Animal Model of Kidney Yang Deficiency Syndrome Using Sex Hormone Application Method

【Animal Modeling】 - Animal Model of Kidney Yang Deficiency Syndrome Using Sex Hormone Application Method

Select female rat offspring born at the same time period for selective breeding. On the 8th day of age, female rats were subcutaneously injected with testosterone propionate at a dose of 1.25mg/animal in the neck and back, and weaned on the 22nd day ...

2023-11-27
【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on the interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2023-11-27
【Animal Modeling】 - Spontaneous Hypertension Rat Model

【Animal Modeling】 - Spontaneous Hypertension Rat Model

Spontaneous hypertensive rats are inbred Wistar rats cultivated by Okamoto and Aoki in 1963 and their control inbred Wistar Kyoto rats. The onset of hypertension in SHR rats is related to an increase in cardiac output. As hypertension progresses, car...

2023-11-23
[Animal Modeling]- Rat Model of High Altitude Erythrocytosis

[Animal Modeling]- Rat Model of High Altitude Erythrocytosis

High altitude polycythemia (referred to as \"hypererythrosis\") is a chronic high altitude disease caused by excessive compensatory proliferation of red blood cells (i.e., excessive proliferation of red blood cells) caused by high altitude ...

2023-11-23
[Animal Modeling ]- Rat Acute Psychological Stress Model

[Animal Modeling ]- Rat Acute Psychological Stress Model

SD rat, 8 weeks old, male. The laboratory temperature is between 18 and 25 ℃, with regular feeding and free diet...

2023-11-23
[Animal Modeling ]- An Animal Model of Cerebral Palsy in Rats

[Animal Modeling ]- An Animal Model of Cerebral Palsy in Rats

Experimental cerebral palsy animal model in neonatal rats after asphyxia...

2023-11-23
[Animal Modeling] - Establishment of a Tree Shrew Hand, Foot, and Mouth Disease Model

[Animal Modeling] - Establishment of a Tree Shrew Hand, Foot, and Mouth Disease Model

Coxsackie virus A16 (CA16) is commonly considered one of the main pathogens of human hand, foot, and mouth disease. The clinical manifestations of hand, foot, and mouth disease in young children include small vesicles in the hands, feet, and mouth, a...

2023-11-23