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【Animal modeling】-Effect of different intervention programs of simvastatin on bone mass in osteoporotic rats

【Animal modeling】-Effect of different intervention programs of simvastatin on bone mass in osteoporotic rats

To explore and compare the intervention effects of simvastatin on bone loss and bone quality decline in ovariectomized rats under different intervention programs...

2023-12-06
[Animal modeling] - Urine metabolomic study on the rat model of abnormal black bile syndrome in Uygur medicine

[Animal modeling] - Urine metabolomic study on the rat model of abnormal black bile syndrome in Uygur medicine

To evaluate and discuss the biological markers of the rat model of abnormal black bile syndrome in Uyghur medicine by combining the observation of external characteristics with the study of urine metabolome...

2023-12-06
【Animal Modeling】-Comparison and Behavioral Evaluation of Rat Spinal Cord Contusion Models

【Animal Modeling】-Comparison and Behavioral Evaluation of Rat Spinal Cord Contusion Models

To establish spinal cord injury models in rats with different degrees of MASCIS and IH, and to study the relationship between injury degree, modeling method, behavior, and anatomical results...

2023-12-06
[Animal modeling] - Establishment of rat lumbar ventral nerve root traction model

[Animal modeling] - Establishment of rat lumbar ventral nerve root traction model

In order to study the pathogenesis of amyotrophic lateral sclerosis and drug development, the rat model of ventral nerve root traction of the fourth lumbar spine was established, and the validity of the model was verified with brain-derived neurotrop...

2023-12-04
[Animal modeling] - Experimental study on the rat model of hypertension combined with hyperlipidemia

[Animal modeling] - Experimental study on the rat model of hypertension combined with hyperlipidemia

To establish a model of spontaneously hypertensive rats (SHR) with hyperlipidemia by feeding them with high-fat diet, and to evaluate their heart and kidney injuries, so as to provide pharmacodynamic animal models and relevant methods for the evaluat...

2023-12-04
【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

To investigate the intervention effect of chitosan on PM2.5-induced acute lung injury in mice...

2023-12-04
【Animal modeling】-Construct a rat COPD-OSAHS overlap syndrome model by smoking and intermittent hypoxia

【Animal modeling】-Construct a rat COPD-OSAHS overlap syndrome model by smoking and intermittent hypoxia

To construct a rat model of COPD-OSAHS overlap syndrome, and to provide a feasible means and experimental platform for basic research on OS...

2023-12-04
[Animal modeling] Establishment of cough variant asthma model in Brown Norway rats

[Animal modeling] Establishment of cough variant asthma model in Brown Norway rats

To establish a simple and practical animal model of cough variant asthma in Brown\\\'s Norway (BN) rats sensitized with ovalbumin (OVA)...

2023-12-04
[Animal modeling] - Study on coagulation function of rat sepsis model

[Animal modeling] - Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in sepsis rat model induced by cecal ligation and puncture...

2023-12-04
[Animal modeling] - Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

[Animal modeling] - Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

To establish a mouse model of endogenous infection induced by intestinal dissemination, so as to provide a reliable experimental model for studying the mechanism of intestinal microecology and endogenous infection...

2023-12-04
【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

Based on the study of the subchronic oral toxicity of diflubenzuron to rats, the effect on the blood system of rats after exposure was preliminarily discussed...

2023-12-04
[Animal modeling] - Study on the relationship between the tree shrew gallstone model and substance P in the digestive tract

[Animal modeling] - Study on the relationship between the tree shrew gallstone model and substance P in the digestive tract

To investigate the relationship between the establishment of tree shrew gallstone model by feeding tree shrews with high cholesterol diet and substance P...

2023-12-02
【Animal Modeling】-Expression of Thrombomodulin in Rat Model of Deep Vein Thrombosis and Its Significance

【Animal Modeling】-Expression of Thrombomodulin in Rat Model of Deep Vein Thrombosis and Its Significance

To observe the expression and significance of thrombomodulin in the natural evolution process of deep vein thrombosis and regression in rats...

2023-12-02
【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...

2023-12-02
[Animal modeling] - Establishment of Bama miniature pig hypertension model induced by high-fat and high-salt diet and its mechanism

[Animal modeling] - Establishment of Bama miniature pig hypertension model induced by high-fat and high-salt diet and its mechanism

To establish the hypertension model of Bama miniature pig with high-fat and high-salt diet and explore its possible pathogenesis...

2023-12-02
[Animal modeling] Establishment of rat model of myocardial cell mitochondrial damage induced by bupivacaine

[Animal modeling] Establishment of rat model of myocardial cell mitochondrial damage induced by bupivacaine

To observe the morphological changes of mitochondria and the production of reactive oxygen species (ROS) in cardiac myocytes induced by electric stimulation of bupivacaine, and to establish an ideal model of rat cardiac myocytes poisoned by bupivacai...

2023-12-02