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【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

To observe the effects of tannin fixation and subsequent treatment on improving the stability of tannin cross-linked bovine jugular vein storage solution, as well as on the thermal stability of blood vessels, anti-calcification ability, biomechanical...

2023-12-14
【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

To investigate the possibility of cabozantinib, a c-Met receptor tyrosine kinase inhibitor, as a novel drug against Listeria monocytogenes infection...

2023-12-14
【Animal Modeling】-Comparison of the effects of restraint and isoflurane anesthesia on the HPA axis of heart rate variability in rats

【Animal Modeling】-Comparison of the effects of restraint and isoflurane anesthesia on the HPA axis of heart rate variability in rats

To observe the changes of heart rate variability in rats under restraint fixation and isoflurane (flow: 0.8L, concentration: 1.5%) anesthesia; and compare the effects of restraint intervention and isoflurane anesthesia on rats by 30min per day for 9...

2023-12-14
【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

To analyze the modeling elements of asthma animal models, and to provide methodological reference for improving the success rate of modeling and evaluating the tested drugs effectively...

2023-12-14
【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

To observe the effects of micro-arc oxidation and alkali treatment on the surface properties, biocompatibility and osteogenic ability of porous tantalum...

2023-12-14
[Animal modeling] Reproduction and identification of sick sinus syndrome disease model constructed by miR-5572 transgenic mice

[Animal modeling] Reproduction and identification of sick sinus syndrome disease model constructed by miR-5572 transgenic mice

To investigate the feasibility of constructing sick sinus syndrome disease model in miR-5572 transgenic mice...

2023-12-14
【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

To investigate the effect of continuous long-term rapid eye movement sleep deprivation (5 d) on depression-like behavior and the level of amygdala monoamine oxidase A in C57BL/6J mice...

2023-12-14
[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

To investigate the pathological changes of subchondral bone and articular cartilage in different animal models of osteoarthritis...

2023-12-13
【Animal modeling】The effect and mechanism of -2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat heart

【Animal modeling】The effect and mechanism of -2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat heart

To investigate the effect and mechanism of contracture inhibitor 2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat hearts...

2023-12-12
【Animal modeling】- Establishment of SD rat limb ischemia-reperfusion injury model

【Animal modeling】- Establishment of SD rat limb ischemia-reperfusion injury model

To introduce an improved method of blocking femoral artery blood flow in vitro, and to establish a simple, controllable and reliable model of limb ischemia-reperfusion injury in rats...

2023-12-12
【Animal Modeling】-Albino C57BL/6N Mice Made by CRISPR-Cas9 Knockout of Tyr Gene

【Animal Modeling】-Albino C57BL/6N Mice Made by CRISPR-Cas9 Knockout of Tyr Gene

To obtain albino C57BL/6N mice and expand their application in skin transplantation and embryonic stem cell research...

2023-12-12
【Animal modeling】-Effect of geniposide on the expression of IL-6, TNF-α and IL-1β in animal models of mastitis

【Animal modeling】-Effect of geniposide on the expression of IL-6, TNF-α and IL-1β in animal models of mastitis

To investigate the effect of geniposide on the expression of IL-6, TNF-α and IL-1β in mammary tissue and mammary epithelial cells of mastitis mice...

2023-12-11
【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

To investigate the expression changes of miR-122 in the kidney tissue of diabetic nephropathy mice and the effect and possible mechanism of silencing miR-122 on the kidney tissue of DN mice...

2023-12-11
【Animal Modeling】-Exploration of the evaluation method of the rat model of precocious puberty with phlegm-damp stagnation syndrome

【Animal Modeling】-Exploration of the evaluation method of the rat model of precocious puberty with phlegm-damp stagnation syndrome

To explore the method of systematic review of the rat model of precocious puberty with phlegm-damp stagnation syndrome...

2023-12-11
【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

Depression, also known as \\\"emotional cold\\\", is a common affective disorder characterized by persistent low mood. The clinical manifestations are depression, loss of various interests and pleasures, and are often accompanied by physica...

2023-12-11
【Animal modeling】-Solanine inhibits the growth of nude mouse prostate cancer cell Du145 xenografts by inducing cell cycle G1/S arrest

【Animal modeling】-Solanine inhibits the growth of nude mouse prostate cancer cell Du145 xenografts by inducing cell cycle G1/S arrest

To investigate the effect and molecular mechanism of solanine on the growth of prostate cancer cell Du145 transplanted in nude mice...

2023-12-08