[Animal Modeling Drug Efficacy Evaluation] - Spontaneous Animal Tumor Model

A type of tumor that naturally occurs in experimental animal populations without conscious artificial experimental treatment is called spontaneous tumor...

2024-09-23

[Animal modeling - Drug efficacy evaluation] - Myocardial ischemia model induced by vascular stenosis controller

Animal: Pitman Moore strain miniature pig, 7 months old, weighing 40kg; Medications: Ketamine, Atropine, Halothane, O2, CO2; Instruments: Surgical instruments, biological function experimental systems, artificial respirators, ameroid resin vascular s...

2024-09-23

[Animal Modeling Drug Efficacy Evaluation] - Preparation of Furazolidone Mouse Cardiomyopathy Model

Wistar rats were treated with 700 × 10 ^ -6 furazolidone added to drinking water (700mg furazolidone per kilogram of water) and observed for 12 weeks...

2024-09-23

[Animal modeling - efficacy evaluation] - diabetes cataract animal model

Fuhashi et al. selected 36 Charles River rats and injected streptozotocin (100mg/kg) intraperitoneally to make diabetes animal models...

2024-09-23

[Animal modeling - efficacy evaluation] - Preparation of diabetes cardiomyopathy model

After feeding a high sugar and high fat diet (10% lard, 20% sucrose, 2% cholesterol, 1% sodium cholate, 67% conventional feed) for 4 weeks, venous blood was collected for fasting (fasting for 10 to 12 hours, during which free drinking water) blood gl...

2024-09-23

[Animal modeling - Drug efficacy evaluation] - Rapid ventricular pacing preparation of canine dilated cardiomyopathy model

Six adult hybrid dogs with a weight of (17.04 ± 2.03) kg were used as experimental animals...

2024-09-23

[Animal Modeling - Pharmacological Evaluation] - Pig Acute Myocardial Ischemia Model

Animal: Experimental miniature pig, both male and female, weighing (16 ± 3.0) kg; Medication: Pentobarbital; Equipment: RM-6008 8-channel physiological recorder...

2024-09-23

[Animal Modeling - Efficacy Evaluation] - Malassezia Infection Animal Model

There are 7 species of filarial parasites that parasitize the human body, of which only Bansheen filarial and Malay filarial are prevalent in China...

2024-09-23

[Animal modeling - Drug efficacy evaluation] - Electrical stimulation induced myocardial ischemia model

Electrical stimulation of the dorsal medial nucleus of the hypothalamus and the optic nerve edge area on the right side of the animal. Stimulation parameters: wave width of 0.2ms, frequency of 50 times/s, weak stimulation (12V) and strong stimulation...

2024-09-23

[Animal Modeling - Efficacy Evaluation] - Animal Model of Fecal Nematode Infection

The fecal roundworm is the only worm that has both complete free living and parasitic generations...

2024-09-23

[Animal modeling - Drug efficacy evaluation] - Coronary artery balloon induced myocardial ischemia model

After anesthetizing the animal, artificial respiration is performed. After opening the chest through the left 4th or 5th intercostal space, the left anterior descending branch of the coronary artery is separated by about 1cm (or a segment of the left...

2024-09-23

[Animal Modeling - Efficacy Evaluation] - Trichinella Infection Animal Model

Trichomoniasis is a zoonotic parasitic disease that can host humans, pigs, mice, cats, dogs, and various wild animals...

2024-09-23

Animal Modeling - Pharmacological Evaluation - Animal Model of Cerebral Arteriovenous Malformation

The previous animal models of cerebral arteriovenous malformations were arteriovenous fistulas without a true malformation mass structure. Massoud et al. established for the first time in 1994 an animal model of cerebral arteriovenous malformation co...

2024-09-20

[Animal Modeling - Pharmacological Evaluation]- Animal Model of Craniocerebral Firearm Injury

Mixed breed dogs, regardless of gender, weighing 15-20kg. After intravenous injection of pentobarbital sodium anesthesia at a dose of 30mg/kg body weight, tracheal intubation was performed. Place the dog on the shooting target platform, fix its head ...

2024-09-20

[Animal Modeling Drug Efficacy Evaluation] - Diffuse and Focal Brain Injury Model in Rats

Organic glass tube: An organic glass tube with a length of 2m, an inner diameter of 19mm, and an outer diameter of 26mm, fixed at 3 points on the wall, with its lower end 15cm above the ground, for placing sponge beds and rats. Drill a small hole wit...

2024-09-20

【Animal Modeling Drug Efficacy Evaluation】 - Chronic Renal Failure Model in 7/8 Renal Resection Rats

Under ether anesthesia, ligate and remove 3/4 of the left kidney through a lumbar incision, and remove the right kidney one week later, for a total of 7/8 kidneys, to establish a chronic renal insufficiency model...

2024-09-20