[Animal modeling] - Optimization of AOM/DSS colon cancer model and exploration of changes in gut microbiota

To optimize the method of modeling colitis associated colon cancer using oxidized azomethane combined with sodium gluconate sulfate and explore the pathogenesis of gut microbiota in CAC...

2024-04-28

Comparison of different regimens in isoproterenol induced chronic heart failure model in animal modeling

To compare animal models prepared with three different regimens and explore a stable, reliable, and reproducible mouse model of chronic heart failure...

2024-04-28

[Animal modeling] - construction and evaluation of a mouse model of chronic restrained intestinal stress injury

Based on the characteristics of social psychological stress leading to inflammatory bowel disease, irritable bowel syndrome, and a series of other diseases, an experimental chronic restraint mouse intestinal stress injury model was established to exp...

2024-04-28

【 Animal Modeling 】 - Inflammation and coagulation dysfunction in a rat model of sepsis with compound infection

To explore the changes in coagulation function and inflammation levels during the course of sepsis...

2024-04-28

[Animal Modeling] - Progress of Tripterygium wilfordii glycoside induced early onset ovarian insufficiency model in mice at different time points

To explore the changes in relevant indicators of early onset ovarian insufficiency (POI) mouse model induced by Tripterygium wilfordii glycosides, and determine the optimal time point for intervention measures...

2024-04-28

【Animal modeling】-Effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats

To study the effect of Astragalus on endoplasmic reticulum stress response (ERS) in vascular remodeling in hypertensive rats, and to explore the molecular mechanism of its vascular protection...

2024-04-27

【Animal Modeling】-The neuroprotective effect of total flavonoids of Mongolian herb Xiangqinglan on Parkinson\\\\\\\\

To investigate the neuroprotective effect of the total flavonoids of Mongolian medicine Xiangqinglan on MPTP-induced Parkinson\\\\\\\\\\\\\\\'s model mice...

2024-04-27

[Animal modeling] - Analysis of the intervention treatment of Taohe Chengqi Decoction on the rat model of hepatic encephalopathy

To investigate the effect of Taohe Chengqi Decoction (without licorice) on hepatic encephalopathy induced by thioacetamide (TAA) in rats...

2024-04-27

【Animal modeling】-Experimental study on loperamide hydrochloride-induced slow transit constipation model in mice

To compare the differences between the models induced by loperamide hydrochloride in slow transit constipation induced by loperamide hydrochloride and different doses and time, and to explore the establishment of a stable loperamide hydrochloride-ind...

2024-04-25

【Animal Modeling】-Preliminary Study on Rhesus Monkey Model Infected by Human Coxsackie B2 Virus

To provide experimental methods and technical support for the establishment of human coxsackie B2 virus infection model in rhesus macaques by preliminarily analyzing the infection characteristics of human coxsackie B2 virus in rhesus monkeys through...

2024-04-25

[Animal modeling] - Establishment and evaluation of an animal model of skin pruritus in guinea pigs

To optimize the dose of histamine and 4-aminopyridine (4-AP) by central composite design response plane method, in order to establish a new model of pruritus in guinea pigs...

2024-04-25

[Animal modeling] - Comparative study on spontaneous and induced type 2 diabetes mouse models

To compare the differences in glucose metabolism, insulin resistance and inflammatory reaction between spontaneous and induced type 2 diabetic mouse models...

2024-04-24

【Animal Modeling】-The role of small animal ultrasound in the diagnosis of thoracic aortic aneurysm/dissection model in mice

To explore a simple and rapid detection method to evaluate whether the mouse model of thoracic aortic aneurysm/dissection was successfully established...

2024-04-24

【Animal modeling】-Efficacy observation and action pathway of Eucommia ulmoides extract on lipopolysaccharide-induced mastitis mice

To study the therapeutic effect and mechanism of Eucommia ulmoides extract on mastitis in mice...

2024-04-23

【Animal Modeling】-Establishment and evaluation of long-term anesthesia protocol for the study of spinal cord injury in rhesus monkeys

To provide a simple and easy anesthesia scheme for the successful establishment of rhesus monkey spinal cord injury model and other long-term surgical operations in rhesus monkeys...

2024-04-22

【Animal modeling】-Protective effect of hemorrhoids magnetized ointment on mouse hemorrhoid model

To study the protective effect of hemorrhoid magnetization ointment on acetic acid-induced hemorrhoids in mice...

2024-04-19