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[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2023-10-18
【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2023-10-18
【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

To investigate the effect of curcumin on glucose transport and phosphatidylinositol kinase-3 (PI3K)/protein kinase B (Akt) signaling pathway in adipocytes of type 2 diabetes mellitus (T2DM) rats...

2023-10-18
[Animal modeling] - Study on the effect of Tongxinluo on the early pathological changes of calcified aortic valvular disease in mice

[Animal modeling] - Study on the effect of Tongxinluo on the early pathological changes of calcified aortic valvular disease in mice

To observe whether Tongxinluo intervention can delay the progression of calcified aortic valvular disease in the early stage...

2023-10-18
[Animal modeling] - chloroform induced arrhythmia model

[Animal modeling] - chloroform induced arrhythmia model

Kunming mice, weighing (35 ± 5) g, both male and female; Drug: chloroform; Equipment: Biological function experimental system...

2023-10-16
[Animal Modeling ]- A Transgenic Animal Model for Tumor Angiogenesis

[Animal Modeling ]- A Transgenic Animal Model for Tumor Angiogenesis

There are many reports on transgenic animal models related to tumor angiogenesis. There are currently three types of transgenic mouse models used for tumor angiogenesis...

2023-10-16
[Animal modeling] - pentobarbital induced acute heart failure model

[Animal modeling] - pentobarbital induced acute heart failure model

(1) Cat acute heart failure model 1. Model making material animal: cat, weighing 2-4kg; Medication: pentobarbital. 2. Method of modeling: After anesthesia with pentobarbital, the animal was subjected to thoracotomy and left ventricular ...

2023-10-16
[Animal modeling] - Propranolol induced heart failure model

[Animal modeling] - Propranolol induced heart failure model

guinea pigs, weighing 250-350g; Medications: pentobarbital, propranolol...

2023-10-16
[Animal modeling] - Escherichia coli endotoxin induced rat uveitis model

[Animal modeling] - Escherichia coli endotoxin induced rat uveitis model

Healthy purebred Wister rats, weighing around 200mg, with endotoxins (ET): the effective component of ET, lipopolysaccharide (LPS), extracted from Escherichia coli with a purity of 99%. Before use, they were dissolved in physiological saline to form ...

2023-10-16
[Animal Modeling] - Swine Heart Failure Model Induced by Rapid Right Ventricular Pacing

[Animal Modeling] - Swine Heart Failure Model Induced by Rapid Right Ventricular Pacing

Healthy Meishan pig, male, weighing 20-25kg; Medications: ketamine, atropine, diazepam, penicillin; Instruments: syringes, surgical instruments, YCP-D pacemakers, ventricular endocardium electrodes...

2023-10-16
[Animal Modeling] - Sleep Deprivation Method for Heart Qi Deficiency Syndrome Animal Model

[Animal Modeling] - Sleep Deprivation Method for Heart Qi Deficiency Syndrome Animal Model

Adult rats were deprived of rapid eye movement phase sleep using small platform water environment technology, and a hopper and water bottle were loaded above the water pool...

2023-10-16
[Animal Modeling] - Elderly Dog Congestive Heart Failure Model

[Animal Modeling] - Elderly Dog Congestive Heart Failure Model

Healthy elderly Northwest hybrid dog, male, with an average age of (8.6 ± 0.7) years and an average weight of (18.6 ± 2.5) kg; Medications: pentobarbital, heparin, penicillin, formaldehyde (40g/L), 76% acetic acid, 10% potassium chloride injection, e...

2023-10-16
[Animal Modeling] - Animal Model of Heart Failure and Heart Qi Deficiency Syndrome Induced by Transplanted Myocardial Infarction

[Animal Modeling] - Animal Model of Heart Failure and Heart Qi Deficiency Syndrome Induced by Transplanted Myocardial Infarction

Adult rats were anesthetized and subjected to tracheal intubation with a ventilator for artificial respiration. The open chest incision was performed, and the left coronary artery was ligated approximately 1mm below the arterial cone and left atrial...

2023-10-16
[Animal Modeling] - Heart Qi Deficiency Cell Model

[Animal Modeling] - Heart Qi Deficiency Cell Model

Myocardial cell culture was conducted in NIH mouse suckling mice 2-4 days after birth. The hearts of the suckling mice were taken and washed in Hank\'s solution. The atria were cut off and repeatedly rinsed to remove residual blood accumulation. The ...

2023-10-16
[Animal Modeling ]- Acute Heart Failure Animal Model

[Animal Modeling ]- Acute Heart Failure Animal Model

Healthy hybrid dog, male and female, with a body weight of (18.54 ± 2.0) kg; Medication: pentobarbital...

2023-10-16
[Animal modeling] - Heart failure model after myocardial infarction in rats

[Animal modeling] - Heart failure model after myocardial infarction in rats

Healthy male SD rats, weighing (200 ± 30) g; Medications: Ether, penicillin...

2023-10-16