动物造模,氯仿诱发心律失常模型 z-bio 2023-10-16 898

　　1. Animal modeling materials: Kunming mice, weighing (35 ± 5) g, both male and female; Drug: chloroform; Equipment: Biological function experimental system.

　　2. Modeling method: First, record the standard II lead electrocardiogram, and then place a 1.5ml chloroform soaked skimmed cotton ball in an anesthesia mask for the animal to inhale. Record the electrocardiogram every half minute to observe changes in heart rhythm.

　　3. Modeling principle: Chloroform induces arrhythmia and establishes an animal model.

　　4. Changes after modeling: The heart rate of the model mice began to slow down at 1 minute, and arrhythmias appeared at 3-4 minutes; At 4.5 minutes, the heart rate began to disappear and ultimately did not recover. Explain the establishment of an arrhythmia model.