[Animal Modeling - Pharmacological Evaluation] - Natural Aging Animal Model of Heart Qi Deficiency Syndrome

Experimental rats were raised for 18 months, and their general conditions such as activity, sleep, mental state, and fur were observed. Changes in body weight, ear temperature, exhaustion swimming time, respiratory rate, heart rate, and heart functio...

2024-08-15

[Animal Modeling Drug Efficacy Evaluation] - Elderly Dog Congestive Heart Failure Model

Animal: Healthy aged Northwest hybrid dog, male, average age (8.6 ± 0.7) years, average weight (18.6 ± 2.5) kg...

2024-08-15

[Animal Modeling Drug Efficacy Evaluation] - Stellay type Interstitial Nephritis Model

Male guinea pig, weighing 400-500g, New Zealand rabbit; Drug: Phosphate buffer solution (pH 7.1), complete Freund\'s adjuvant...

2024-08-15

【Animal modeling - Drug efficacy evaluation】 - Chronic serum nephritis

rabbit; Drug: Bovine serum albumin (BSA)...

2024-08-12

[Animal Modeling - Pharmacological Evaluation] - Vibrio cholerae endotoxin induced uveitis model in rats

Preparation of endotoxins: Vibrio cholerae 18001 strain, classical biotype, Ogawa serotype. ① The purified Vibrio cholerae species that have been identified will be first transferred from the inclined surface of the Houttuynia cordata to the Houttuyn...

2024-08-09

[Animal Modeling - Pharmacological Evaluation] - Bloodletting plus Propranolol Heart Qi Deficiency Animal Model

Adult rats were placed in a 30 ℃ environment for 1 hour, and their tails were cut 0.3-0.5cm and immersed in 37 ℃ warm water. Accurate quantification was performed using a graduated cylinder until 5ml of blood was lost, twice a day, for a total of 10 ...

2024-08-09

[Animal Modeling Drug Efficacy Evaluation] - Escherichia coli endotoxin induced rat uveitis model

Healthy purebred Wister rats, weighing around 200mg, were treated with endotoxin (ET): the active ingredient of ET, lipopolysaccharides (LPS), extracted from Escherichia coli with a purity of 99%. Before use, the rats were dissolved in physiological ...

2024-08-09

[Animal Modeling - Pharmacological Evaluation] - Propranolol induced Heart Failure Model

guinea pig, weighing 250-350g; Medications: Pentobarbital, Propranolol...

2024-08-09

[Animal Modeling - Pharmacological Evaluation] - Acute Heart Failure Model Induced by Pentobarbital

cat, weighing 2-4 kg; Drug: Pentobarbital...

2024-08-09

[Animal modeling - Drug efficacy evaluation] - Anesthetic induced bradycardia model

Adult mice weighing 25-40g; Drug: 10% urinary ester; Equipment: Biological function experimental system...

2024-08-09

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Postoperative Metastasis of Human Tumors

It is difficult to establish a subcutaneous transplant tumor metastasis model mainly because the tumor is implanted subcutaneously, and its microenvironment is not conducive to the expression of malignant tumor biological characteristics, especially ...

2024-08-09

[Animal modeling - Drug efficacy evaluation] - Central electrical stimulation induces arrhythmia

rabbit, weighing about 2.5kg, both male and female; Medications: Chloralose, Uratan, Chlorosuccinylcholine; Equipment: Biological function experimental system, stereotaxic instrument...

2024-08-09

[Animal Modeling - Efficacy Evaluation] - Liver Cancer Transgenic Animal Model

The experimental animals used to establish liver cancer transgenic animal models are often CD1, C57BL/6 × DBA, C57BL/6 × SJL and other strains of mice...

2024-08-09

[Animal modeling - Drug efficacy evaluation]- Serum nephritis model

rabbit; Drug: Bovine serum albumin (BSA)...

2024-08-09

【Animal Modeling - Pharmacological Evaluation】 - Chronic Glomerulonephritis Model

monkey, weighing 2.2-2.4kg; Drug: glomerular basement membrane, complete Freund\'s adjuvant...

2024-08-09

[Animal modeling - Drug efficacy evaluation] - Autoimmune liver disease

BALB/c mice, 15-20g, diluted with PBS to 2mg/ml of adzuki bean protein A, and injected via tail vein at 10-20mg/kg. Liver injury can occur after 8 hours...

2024-08-07