[Animal modeling - Efficacy evaluation] - Vaginal inoculation of Chlamydia trachomatis (CT) model

Barron et al. first inoculated female mice with Chlamydia trachomatis pneumonia into their vagina, successfully infecting them with MoPn. Chlamydia inclusion bodies were visible on cervical smears, and antibody responses were observed in serum...

2024-08-19

【Animal Modeling - Efficacy Evaluation】 - Animal Model of Lyme Disease Infection in Dogs

Select dogs without other pathogen infections, aged 6-8 weeks, with separate rooms for each animal, fed with commercial feed, and sterile drinking water...

2024-08-19

[Animal modeling drug efficacy evaluation] - Chronic local cerebral ischemia model induced by middle cerebral artery infarction in rats

Male SD rats weighing 280-350g; Medications: Chloral hydrate, antibiotics...

2024-08-19

[Animal Modeling - Pharmacological Evaluation]- Mouse Low Temperature Swimming Cerebral Ischemia Model

Attach a rubber ball equivalent to 5% of body weight to the tail 2mm away from the tail root, swim in water at 10-10.5 ℃ for 5 minutes, and remove it. Quickly cut the head with large scissors and record the breathing time of the cut...

2024-08-19

[Animal Modeling - Pharmacological Evaluation] - Three Cerebral Arterial Blockage Models in Rats

After animal anesthesia, ligate the basal artery, then clamp the bilateral common carotid arteries with arterial clips. After a certain period of time, remove the bilateral common carotid arteries and restore blood flow...

2024-08-19

Animal modeling - Drug efficacy evaluation - Closing four blood vessels in animals to induce cerebral ischemia model

Animal: Rat; Medications: Anesthetics, Antibiotics; Equipment: Electric Condenser...

2024-08-19

[Animal Modeling - Pharmacological Evaluation] - Lipopolysaccharide induced Brain Edema Model in Juvenile Mice

Animal: Healthy Wistar rats, weighing 70-100g, male or female not limited; Drug: Lipopolysaccharide...

2024-08-19

[Animal modeling - Drug efficacy evaluation] - pertussis bacterial solution induced cerebral edema model in rabbits

Animal: Healthy rabbit, weighing 1.75-2.15 kg; Medications: Anesthetics, pertussis bacterial fluid...

2024-08-19

[Animal Modeling Drug Efficacy Evaluation] - Typhimurium Lipopolysaccharide Induced Cerebral Edema Model in Rabbits

rabbit; Medications: Anesthetic, typhoid lipopolysaccharide, 2.5% Evans blue saline solution; Equipment: Brain pressure gauge, multi-channel physiology instrument...

2024-08-19

[Animal Modeling - Pharmacological Evaluation] - Olive Oil Induced Cerebral Edema Model in Rabbits

rabbit; Medication: Anesthetic, olive oil, 2.5% Evans blue saline solution; Equipment: Brain pressure gauge, multi-channel physiology instrument...

2024-08-19

[Animal Modeling Drug Efficacy Evaluation]- Enterohemorrhagic Escherichia coli Mouse Infection Model

Normally, mice are not sensitive to wild-type EHEC O157: H7 infection. Adult mice of IQI, BALB/c, KM, and other strains are not susceptible to O157. Vaccination with live EHEC O157 EDL933W (NalR) at a dose of 10 ^ 10 to the power of 10 did not cause ...

2024-08-19

[Animal Modeling - Pharmacological Evaluation] - Sucrose Induced Hypertension Rat Model

SD rats, weighing 142-180g; Drug: Sucrose...

2024-08-19

[Animal modeling - efficacy evaluation] - Preparation of non-human primate tuberculosis model

The non-human primate tuberculosis model is the closest animal model of tuberculosis to human tuberculosis...

2024-08-19

[Animal Modeling - Pharmacological Evaluation] - Adenosine induced Chronic Renal Failure in Rats with Hypertension Model

SD male rats weighing 150-190g; Drug: Adenosine, molecular weight 135.13...

2024-08-19

[Animal modeling - efficacy evaluation] - Preparation of tuberculosis free model

In the past, the preparation of rabbit tuberculosis models was mainly intravenous infection, but now aerosol infection is the most commonly used method...

2024-08-19

[Animal Modeling Drug Efficacy Evaluation] - HLA-B2704 Transgenic Mouse Spontaneous Anterior Uveitis Model

F1 generation was obtained by mating genetically modified positive mice, and F2 generation was obtained by mating sisters. The experimental animals include the first genetically modified mice, F1 and F2 generations...

2024-08-15