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【Animal modeling】 - Ammonium chloride induced pulmonary edema animal model

【Animal modeling】 - Ammonium chloride induced pulmonary edema animal model

Animals in the modeling group were intraperitoneally injected with 0.6ml/100g of ammonium chloride (rat, drug concentration 6%), 0.15ml/10g of body weight (mouse, drug concentration 3%), and 0.5-0.7ml/kg (guinea pig, drug concentration 6%)...

2024-06-03
[Animal modeling] - Establishment of a mouse model of adverse skin reactions induced by erlotinib

[Animal modeling] - Establishment of a mouse model of adverse skin reactions induced by erlotinib

Elotinib is a new targeted drug for the treatment of non-small cell lung cancer. In recent years, it has been widely used in clinical practice, but there are many side effects, among which rash is the most common, and it is most difficult for patient...

2024-06-03
【Animal modeling】-Effect of metformin on cognitive dysfunction and PI3K/Akt pathway in Alzheimer\\\\\\\\\\\\\\\\

【Animal modeling】-Effect of metformin on cognitive dysfunction and PI3K/Akt pathway in Alzheimer\\\\\\\\\\\\\\\\

To investigate the effect of metformin on phosphatidylinositol-3-kinase/protein kinase B pathway and cognitive dysfunction in Alzheimer\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s disease rats...

2024-06-03
[Animal modeling] - Comparison of effects of different exercise modes on MSTN and IGF1 of skeletal muscle in rats

[Animal modeling] - Comparison of effects of different exercise modes on MSTN and IGF1 of skeletal muscle in rats

To explore the effects of different exercise modes on MSTN and IGF1 of skeletal muscle in rats, and provide theoretical basis for selecting appropriate exercise modes to improve skeletal muscle function...

2024-06-03
【Animal Modeling】-A study on the combination of disease and syndrome of atherosclerosis (Qi stagnation and blood stasis syndrome) in rats

【Animal Modeling】-A study on the combination of disease and syndrome of atherosclerosis (Qi stagnation and blood stasis syndrome) in rats

To construct a rat model of atherosclerosis combined with disease and syndrome, and to provide an evaluation tool for the pharmacodynamics study of the corresponding traditional Chinese medicine...

2024-06-03
[Animal modeling] - Establishment of long-term survival rat model of moderate and severe sepsis

[Animal modeling] - Establishment of long-term survival rat model of moderate and severe sepsis

To establish a long-term survival rat model of moderate and severe sepsis, observe the natural course of sepsis, and provide new ideas and methods for the study of sepsis...

2024-06-03
[Animal Modeling] - Based on SDF-1/CXCR4 axis, observe the effect of Jisheng Shenqi Decoction on the homing of BMSCs in cirrhotic rats

[Animal Modeling] - Based on SDF-1/CXCR4 axis, observe the effect of Jisheng Shenqi Decoction on the homing of BMSCs in cirrhotic rats

To investigate the effect of Jisheng Shenqi Decoction on the homing efficiency of bone marrow mesenchymal stem cells through the 4 axis of stromal cell derived factor-1/CXC chemokine receptors, and to analyze the mechanism of its combination with BMS...

2024-05-31
【Animal Model】-Experimental stress-induced impairment of mouse welfare and the effect of music intervention

【Animal Model】-Experimental stress-induced impairment of mouse welfare and the effect of music intervention

To explore the degree of damage to animal welfare caused by routine experimental operations and the effect of music intervention...

2024-05-31
【Animal modeling】-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

【Animal modeling】-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

To study the dynamic changes and significance of oxidative stress and cytokines in the formation of nonalcoholic fatty liver disease (NAFLD) in gerbils...

2024-05-31
[Animal Modeling ]- Persistent Regional Cerebral Ischemia Model Induced by Middle Cerebral Artery Infarction in Rats

[Animal Modeling ]- Persistent Regional Cerebral Ischemia Model Induced by Middle Cerebral Artery Infarction in Rats

Male SD rats, weighing 280-350g; Medication: Chloral hydrate, antibiotics...

2024-05-31
【Animal Modeling】-Effect of Maiqi Jiangtang Pill on blood sugar in ob/ob mice

【Animal Modeling】-Effect of Maiqi Jiangtang Pill on blood sugar in ob/ob mice

To study the effect of Maiqi Jiangtang Pills on blood sugar in ob/ob mice...

2024-05-28
[Animal modeling] - Targeting recognition of heptamethine cyanine near-infrared fluorescent dye on orthotopic transplantation model of gastric cancer

[Animal modeling] - Targeting recognition of heptamethine cyanine near-infrared fluorescent dye on orthotopic transplantation model of gastric cancer

To study the effect of heptamethine cyanine near-infrared fluorescence (NIRF) dye in vivo imaging of orthotopic gastric cancer transplantation model...

2024-05-28
【 Animal modeling 】 - Repeated immune induction of ulcerative colitis in rats

【 Animal modeling 】 - Repeated immune induction of ulcerative colitis in rats

Animal modeling materials: Adult rats, male and female, weighing 250-400g; Medications: physiological saline, formaldehyde...

2024-05-28
【Animal Modeling】-Comparison of Two Ways of Respiratory Infection to Establish Mouse Influenza Virus Infection Model

【Animal Modeling】-Comparison of Two Ways of Respiratory Infection to Establish Mouse Influenza Virus Infection Model

To explore the differences in the establishment of mouse influenza virus infection models through two different respiratory tract infection methods, and to provide reference for the selection of appropriate animal infection models for the study of in...

2024-05-28
【Animal Modeling】-Study on the characteristics of spontaneous hindlimb paralysis in hyperlipidemia-susceptible (WSHc) rats

【Animal Modeling】-Study on the characteristics of spontaneous hindlimb paralysis in hyperlipidemia-susceptible (WSHc) rats

Observe the etiology and pathological characteristics of hyperlipidemia (WSHc) rats with spontaneous hindlimb paralysis, study the etiology in advance, and explore its application and scientific research value...

2024-05-27
[Animal Modeling] - Rabbit Lung Candida albicans Infection Model

[Animal Modeling] - Rabbit Lung Candida albicans Infection Model

36 New Zealand white rabbits with large ears, 18 in the experimental group and 18 in the control group. On the first to fifth days of the experiment, 440 mg/m2 of cytarabine was injected into the ear vein daily, and the immunosuppressive state was ma...

2024-05-23