[Animal modeling] - Construction and identification of a humanized mouse model immunized with prostate cancer

To construct a humanized mouse model of immune system and transplant it into a human prostate cancer cell line for the study of immunotherapeutic drugs for prostate cancer...

2022-12-15

[Animal modeling] - Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

To explore the effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia (FD)...

2022-12-14

[Animal modeling] - Study on the improvement effect and mechanism of paeoniflorin on Bayk8644 induced depression and anxiety like behavior in rats

To explore the pharmacological mechanism of paeoniflorin in improving depression and anxiety like behavior in rats based on L-type voltage dependent calcium channel...

2022-12-14

[Animal modeling] - Effect of Spirillum hepaticum infection on chronic colitis model induced by dextran sodium sulfate in mice

To investigate the effect of Spirillum hepaticum infection on chronic colitis induced by dextran sodium sulfate in mice...

2022-12-14

[Animal modeling]- α- Effect of Roxnipin on Immune Function in Immunosuppressive Mice

discussion α- The effect of Roxniphyllin on the immune function of the immunosuppressive model of mice induced by cyclophosphamide provides an experimental basis for the follow-up mechanism research and the development of new drugs to increase immune...

2022-12-14

[Animal modeling] - Acupuncture can improve the symptoms of insomnia rats and affect their spontaneous activities by regulating GABA Gln metabolism

To study the effect of acupuncture on the improvement of symptoms and spontaneous activities in insomnia rats, and explore its possible mechanism...

2022-12-13

[Animal modeling] - Inhibitory effect of cytomegalovirus on some immune indexes of mice implanted with polymethylmethacrylate

To study the inhibitory effect of cytomegalovirus (CMV) on immune response of mice implanted with polymethyl methacrylate (PMMA)...

2022-12-13

[Animal modeling] - Protective effect of curcumin on acute renal injury in rats with pregnancy induced hypertension

To investigate the protective effect of curcumin on acute renal injury induced by pregnancy induced hypertension in rats and explore its potential mechanism...

2022-12-13

[Animal modeling] - Experimental study on lung tissue damage in rats caused by dental grinding dust

To evaluate the effects of cobalt chromium molybdenum metal , zirconia porcelain and polymethyl methacrylate resin on lung injury in rats...

2022-12-13

[Animal modeling] - Effect of metformin regulating miR-34a on airway inflammation in COPD rats

To investigate the effects of metformin (Met) on airway inflammation in rats with chronic obstructive pulmonary disease (COPD)...

2022-12-13

[Animal modeling] - Relevant changes of rat uterine ligament fibroblasts induced by hydrogen peroxide in vitro

To investigate the effects of oxidative stress on the proliferation, apoptosis, collagen synthesis and the expression of inflammatory factors of uterine ligament fibroblasts...

2022-12-13

[Animal modeling] - The protective effect of regular aerobic exercise on the brain of rats with cerebral ischemia and its mechanism

To study the protective mechanism of regular aerobic exercise on brain tissue of rats with cerebral ischemia...

2022-12-13

[Animal modeling] The expression and mechanism of miR-122 in the kidney tissue of diabetes mice

To investigate the expression of miR-122 in renal tissue of diabetes nephropathy mice and the effect of silencing miR-122 on renal tissue of DN mice and its possible mechanism...

2022-12-13

[Animal modeling] - Study on the protective effect of etomidate based on TLR4 pathway on acute lung injury in rats with septic shock

To investigate the protective effect of etomidate (Eto) based on Toll like receptor 4 (TLR4) pathway on acute lung injury in septic shock rats...

2022-12-13

[Animal modeling] - Effect and mechanism of androgen on mitochondrial function of gastric mucosa in aged rats

To investigate the effect of androgen on mitochondrial function of gastric mucosa in aged rats with testicular resection (GDX) and its mechanism...

2022-12-13

[Animal modeling] - Intervention effect of chitosan on acute lung injury induced by PM2.5 in mice

To investigate the intervention effect of chitosan on acute lung injury induced by PM2.5 in mice...

2022-12-12