[Animal modeling] - Effect and mechanism of androgen on mitochondrial function of gastric mucosa in aged rats

To investigate the effect of androgen on mitochondrial function of gastric mucosa in aged rats with testicular resection (GDX) and its mechanism...

2022-12-27

[Animal modeling] - Mechanism of protective effect of desmophilin A on liver ischemia-reperfusion in rats

To investigate the protective mechanism of Rhizoma Caryophylli A (RA) on hepatic ischemia-reperfusion injury in rats...

2022-12-27

[Animal modeling] - Experimental study on the adhesive and antioxidant effects of mussel mucin on ulcerative colitis in rats

To observe the effect of mussel mucin (MAP) on intestinal mucosa of rats with ulcerative colitis, and to explore its mechanism from the perspective of adhesion and antioxidation...

2022-12-27

[Animal modeling] - Analysis of gentiopicrin on tumor growth inhibition and anti angiogenesis in H22 hepatoma mice

To investigate the inhibitory effect of gentiopicrin on tumor growth and anti angiogenesis mechanism in H22 hepatoma mice...

2022-12-27

[Animal modeling] - The neuroprotective effect of total flavonoids of Mongolian medicine Cymbidium album on Parkinson\'s disease model mice

To investigate the neuroprotective effect of total flavonoids from Mongolian medicine Cymbidium album on MPTP induced Parkinson\'s model mice...

2022-12-27

[Animal modeling] - To explore the neuroprotective effect of DAHP on brain injury rats based on NOS pathway

To explore the neuroprotective effect of 2,4-diamino-6-hydroxypyrimidine (DAHP) on brain injury in rats and its possible mechanism...

2022-12-27

[Animal modeling] - Effect of astragalus saponin Ⅱ on IL-21/STAT3 pathway and airway inflammation in asthmatic young rats

To investigate the effects of astragalus saponin Ⅱ on interleukin-21 (IL-21)/signal transducer and activator of transcription 3 (STAT3) pathway and airway inflammation in asthmatic young rats...

2022-12-27

[Animal modeling] - Effect of microcystin LR on mitochondrial function of primary mouse hepatocytes

Microcystin pollution caused by cyanobacteria blooms is one of the topics of worldwide concern...

2022-12-27

[Animal modeling] - Neuroprotective effect and mechanism of Dendrobium nobile on MPTP induced PD mice

to investigate the neuroprotective effect of dendrobium nobile extract on parkinson\'s disease model induced by 1-methylv-4-phenyl-1,2,3,6-tetrahydropyridine in mice...

2022-12-26

[Animal modeling] - The improvement effect of Baixiangdan capsule on premenstrual anxiety caused by ovariectomy in rats

To compare the intervention effects of Baixiangdan capsule (BXD), 5-HT3R specific agonist and its antagonist, and cannabinoid receptor 1 (CB1R) specific agonist and its antagonist on premenstrual dysphoria and anxiety rats through a series of behavio...

2022-12-26

[Animal modeling] - Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

To analyze the protective effect of amygdalin on necrotizing enterocolitis in neonatal rats...

2022-12-26

[Animal modeling] - Observation on the anesthetic effect of different doses of Zoletil combined with Serazine hydrochloride on C57BL/6J mice

Objective C57BL/6J mice were anesthetized with different doses of Zoletil combined with Cyperazine hydrochloride to observe the anesthesia related time of mice under different anesthetic doses, so as to provide reference for various mouse operations ...

2022-12-26

[Animal modeling] - Based on 16S rRNA sequencing, analyze the effects of two reoviruses on intestinal flora of mice

To investigate the effects of T1L and NBV reovirus on intestinal flora in mice...

2022-12-26

[Animal modeling] Effect of low expression of lipoic acid synthase on antioxidant capacity of mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene and detect its antioxidant capacity...

2022-12-26

[Animal modeling] - Effect of Jiayankangtai Granule on immune related cytokines in rats with autoimmune thyroiditis

To investigate the effect of Jiayankangtai Granule on immune related cytokines in rats with autoimmune thyroiditis, and explore the mechanism of Jiayankangtai Granule in improving autoimmune thyroiditis...

2022-12-26

[Animal modeling] - Transcriptome analysis of colon tissue in IBD mice under the intervention of mesalazine

To detect the changes of gene expression in colon tissue of mice with inflammatory bowel disease (IBD) by transcriptome sequencing, and to improve the understanding of the molecular mechanism of mesalazine in the treatment of IBD...

2022-12-26