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【Animal Modeling】-Pathological Study of Spontaneous Hepatobiliary Hyperplasia in Aged Rats

【Animal Modeling】-Pathological Study of Spontaneous Hepatobiliary Hyperplasia in Aged Rats

To accumulate valuable research data on rat hepatic bile duct hyperplasia for related scientific research and new drug safety evaluation...

2023-03-24
【Animal Modeling】-Discussion on the anatomical structure of the blood vessels of the rat tail and the physiological function of the rat tail

【Animal Modeling】-Discussion on the anatomical structure of the blood vessels of the rat tail and the physiological function of the rat tail

Through the anatomical study of the tail blood vessels of experimental rats, to further clarify the course and distribution of the arteries and veins, to deepen the understanding of their physiological functions, and to provide an anatomical basis fo...

2023-03-24
【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

To detect the correlation between the SNP locus of SLCIA2 gene and the activity of Labrador retrievers and golden retrievers, in order to screen effective genetic molecular markers for the early selection and breeding of guide dogs...

2023-03-24
【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

To investigate the mechanism of transplantation of human umbilical cord mesenchymal stem cells (hUCMSCs) to restore ovarian function in rats with premature ovarian failure...

2023-03-24
【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

To establish an animal model of high-fat diet-induced non-alcoholic fatty liver disease in cynomolgus monkeys, to analyze the effect of high-fat diet feeding time on the formation of NAFLD in animals, and to explore the relationship between high-fat...

2023-03-24
【Animal modeling】-Construction of inhibin gene knockout mouse model and preliminary analysis of phenotype

【Animal modeling】-Construction of inhibin gene knockout mouse model and preliminary analysis of phenotype

To construct an inhibin knockout mouse model by gene editing technology of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) and preliminary analysis of its phenotype...

2023-03-24
【Animal Modeling】-Retinal Morphology and Expression of RhoA and ROCK-2 in Rats with Ocular Ischemia Syndrome

【Animal Modeling】-Retinal Morphology and Expression of RhoA and ROCK-2 in Rats with Ocular Ischemia Syndrome

To establish a rat model of ocular ischemia syndrome (OIS) and observe the retinal morphology and the differences in the expressions of RhoA and ROCK-2 in rat retina after ischemia...

2023-03-23
【Animal Modeling】-Protective effect of camel milk on DSS-induced acute enteritis in mice

【Animal Modeling】-Protective effect of camel milk on DSS-induced acute enteritis in mice

To explore the protective effect of camel milk on dextran sulfate sodium (DSS)-induced acute enteritis in mice...

2023-03-23
【Animal modeling】-neural function and histomorphological changes of the jejunum of early type 1 diabetic rats

【Animal modeling】-neural function and histomorphological changes of the jejunum of early type 1 diabetic rats

To investigate the function of nitrergic and cholinergic nerves in jejunal smooth muscle and the morphological changes of jejunum in early stage type 1 diabetic rats...

2023-03-22
[Animal modeling] - Study on the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury in rats

[Animal modeling] - Study on the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury in rats

To investigate the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury (LIRI) in rats...

2023-03-21
[Animal modeling] - Interventional effect and possible mechanism of resveratrol on premature ovarian failure in mice

[Animal modeling] - Interventional effect and possible mechanism of resveratrol on premature ovarian failure in mice

To observe the intervention effect of resveratrol on premature ovarian failure in mice and elucidate its possible mechanism...

2023-03-21
[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in propofol anesthetized rats

[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in propofol anesthetized rats

To explore the effects of different exercise modes on skeletal muscle growth factors MSTN and IGF1 in rats, and to provide theoretical basis for selecting appropriate exercise modes to improve skeletal muscle function...

2023-03-21
[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior in female rats

[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior in female rats

To investigate the effects of arginine vasopressin 1b receptor gene knockout on plasma corticosterone content, anxiety, and social behavior in female rats...

2023-03-21
【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2023-03-20
[Animal Modeling] - Study on the Mechanism of Intermittent Fasting in Improving Metabolic Disorders Induced by Olanzapine in Mice

[Animal Modeling] - Study on the Mechanism of Intermittent Fasting in Improving Metabolic Disorders Induced by Olanzapine in Mice

To investigate the protective effect and mechanism of intermittent fasting on metabolic disorders induced by olanzapine in mice...

2023-03-20
[Animal modeling] - Inhibition of miR-146b-5p expression in situ improves renal fibrosis in UUO mice

[Animal modeling] - Inhibition of miR-146b-5p expression in situ improves renal fibrosis in UUO mice

To investigate the expression of miR-146b-5p in a mouse model of renal fibrosis, and to investigate the effect of knocking down miR-146b-5p in vivo on renal injury and fibrosis in mice...

2023-03-20