To compare the hepatotoxicity of matrine and oxymatrine, to explore the severity and characteristics of their toxicity, and to preliminarily clarify the toxicity mechanism?...
2023-06-05The purpose of this experiment was to investigate the effect and mechanism of fine particulate matter PM2.5 on ApoE knockout (Apoe-/-) mice (atherosclerosis model mice)...
2023-06-02To observe the protective effect of Danggui Buxue Decoction on mice irradiated by 60C0-γ ray...
2023-06-02To study the pathogenic mechanism and drug development of amyotrophic lateral sclerosis, establish a rat model of pulling the fourth lumbar ventral nerve root, and use brain-derived neurotrophic factor as a positive drug to verify the effectiveness o...
2023-06-02After human tumors are implanted subcutaneously, tumor cells are not easy to invade surrounding tissues, because envelopes are often formed around the graft, and the same tumor cells are not easy to penetrate into the abdominal cavity or other tissue...
2023-06-01To observe the survival curve of Presenilin-1/Presenilin-2 double knockout mice (dKO mice), and to provide a reference for further reproduction and the use of this model for the study of Alzheimer\\\'s disease (AD)...
2023-06-01To establish an efficient and reliable strategy for the isolation and expansion of mouse spleen mesenchymal stem cells by tissue block culture method...
2023-06-01Gastroesophageal reflux refers to the reflux of gastric contents (such as bile salts and pancreatin) that flows from the duodenum into the stomach and enters the esophagus. It is divided into physiological reflux and pathological reflux...
2023-06-01Monocrotaline (MCT) is a plant extract of the genus Crotalaria. It is a double-layer pyrrolidine alkaloid that can carbonize the DNA of cancer cells and exert anti-cancer effects, mainly after injection in the body...
2023-06-01To establish a mouse model of mechanical lung injury by ventilator hyperventilation, intervene with angiotensin II receptor inhibitor losartan, and explore the effect of losartan on caveolin-1 in the lung of mice with mechanically ventilated lung inj...
2023-05-31To study the similarities and differences in growth and reproduction between Tlr4 knockout mice and KM mice...
2023-05-31Explore the effects of anesthetics in different animal experiments on the cardiovascular system of rats...
2023-05-31Understand the effect of Gehua Jiejiu Dizhi Decoction on liver fat deposition in alcoholic fatty liver (AFLD) mice, and observe its effect on liver tissue pregnane receptor (PXR) and its regulatory target genes CYP3A11 and CYP3A25 proteins...
2023-05-31To detect the differences in the expression of proteomes in the liver tissue of male and female mice, and to explore the mechanism of gender differences in the occurrence of liver diseases...
2023-05-31To analyze the structure and composition of E. coli bacteria in tree shrew by high-throughput sequencing technology...
2023-05-30To investigate the relationship between the protective effect of propofol on cerebral ischemia-reperfusion injury and gap junctions and its possible mechanism...
2023-05-30