[Animal modeling] - Observation on the effect of Lumianning Ⅱ and ketamine combined with propofol on the experimental pigs undergoing endoscopic surgery via natural cavity

To observe the anesthetic effect of induced anesthetics Lumianning Ⅱ or ketamine combined with propofol on experimental pigs undergoing the placement of gastric gallbladder stent for bile conservation and lithotomy through the natural lumen endoscopi...

2024-01-12

【Animal modeling】-Effect of curcumin on Keap1/ARE signaling pathway and bile acid enterohepatic circulation in liver cancer model mice

To investigate the effect of curcumin on cytoplasmic protein chaperone (Keap1)/antioxidant response element (ARE) signaling pathway and bile acid enterohepatic circulation in liver cancer model mice...

2024-01-12

[Animal modeling] - The neuroprotective effect of tanshinone IIA on Alzheimer\'s disease model mice and its impact on the PI3K/AKT pathway

To investigate the neuroprotective effect of tanshinone IIA (Tan IIA) on Alzheimer\\\\\\\'s disease (AD) model mice and its effect on phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) pathway...

2024-01-12

【Animal modeling】-Bakuchiol for the treatment of castration-induced osteoporosis in male mice

To observe the therapeutic effect of bakuchiol on castration-induced osteoporosis in male mice...

2024-01-12

【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat renal cells induced by high glucose...

2024-01-12

【Animal modeling】-Exploration of nutritional intervention measures during long-distance transportation of tree shrew

To explore appropriate nutritional intervention methods to reduce the adverse effects of stress response caused by long-distance transportation on experimental tree shrew...

2024-01-11

【Animal Modeling】-Protective effect of Patrinia on acetaminophen-induced drug-induced liver injury in rats

Paijiangcao is the whole rooted herb of the perennial herbs of the family Paiaceae, Huanghuabaijiang and Baihuabaijiang, with various pharmacological activities. The purpose of this study was to investigate the protective effect of Patrinia on acetam...

2024-01-11

【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

To explore the therapeutic effect of anti-complement 5a receptor (C5aR) antibody combined with allicin on inflammatory bowel disease (IBD) in rats...

2024-01-11

【Animal modeling】-Development and preliminary application of a waste gas treatment device for experimental animal facilities

To develop a device suitable for waste gas treatment in laboratory animal facilities, and to verify the effect through field application...

2024-01-11

Mammalian brain development is a complex and orderly process that is highly precisely regulated

Mammalian brain development is a complex and orderly process that is highly precisely regulated...

2024-01-11

【Animal modeling】-Streptozotocin-induced diabetic rat model changes in intestinal flora

To observe the changes in the structure and abundance of intestinal flora in streptozotocin-induced diabetic rat model...

2024-01-10

【Animal Modeling】-SPF Bama miniature pig breeding and application

Miniature pigs have greater similarities with humans in terms of body shape, size, physiology and disease development. They are ideal experimental animal models. They are exploring the laws of human life activities and studying the pathogenic mechani...

2024-01-10

【Animal modeling】-Analysis of ammonia gas and heavy metal content in drinking water of cynomolgus monkeys

To detect the ammonia concentration and heavy metal content in drinking water in the monkey house of cynomolgus monkey breeding base...

2024-01-10

【Animal modeling】-Effect of deoxycholic acid on the growth of ileal organoids in C57BL/6 mice

To investigate the changes in the structure of intestinal flora in quail with hyperuricemia, and to provide reference for the study of the pathological mechanism of hyperuricemia...

2024-01-10

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on the interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2024-01-10

【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

By observing the effects of tacrolimus on blood glucose, insulin levels, hepatic tissue protein phosphatase 2A and phosphorylated AKT expression in rats, to further explore the mechanism of tacrolimus-induced blood glucose elevation...

2024-01-10