动物造模,药效评价,肾病 z-bio 2024-08-27 338

　　1. Modeling material animals: male rabbits weighing 2-2.5kg; Drug: mercuric chloride.

　　2. Modeling method: Animals are subcutaneously injected with 0.75-0.80ml of 1% mercury solution every day for 3-5 consecutive days.

　　3. Modeling principle: Mercury poisoning causes kidney disease in rabbits.

　　4. Changes after modeling can lead to kidney disease and reduced urine output. After 5 days, the model stabilized.