动物造模,溃疡模型 z-bio 2023-10-23 1072

　　1. Model making material animals: rats, weighing 180-260g; Medication: Histamine phosphate.

　　2. Method of modeling: Rats fasted for 24 hours, and were subcutaneously injected with 30mg/kg of histamine phosphate into the abdomen. After 2 hours, they were injected again, and the animals were killed after 3 hours.

　　3. Modeling principle: Drugs cause ulcers in animals.

　　4. Changes after modeling: Ulcers can occur in the esophagus, stomach, duodenum, and other tissues of animals after modeling.